Cyclin D is a proto-oncogene that is necessary for entry into the S stage of the cell cycle. When bound to the correct kinase, RB is modified, and…

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Cyclin D is a proto-oncogene that is necessary for entry into the S stage of the cell cycle. When bound to the correct kinase, RB is modified, and cell division is promoted. Then, cyclin D is destroyed. How might a mutation in cyclin D lead to uncontrolled cell growth?

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